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Herpes Simplex Virus Infections in Pregnant Women and Neonates

Source: www.herpes-foundation.org
Topic: Herpes
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Sort Desciption: Neonatal herpes is a severe disease associated with a high degree of morbidity and mortality and long-term serious consequences in survivors. Neonatal herpes presents in several different forms: ...

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Approximately 80% of the adult population of the United States is infected with herpes simplex virus (HSV). HSV infections are underrecognized by both physicians and patients, leading to transmission of the disease to sexual partners and neonates. Ninety percent of herpes infections in neonates are acquired from exposure to an active maternal HSV infection at the time of delivery. Five percent are acquired congenitally, and the remaining 5% of infected neonates contract HSV from a nonmaternal source, such as the father, grandparent, or nurse. Neonatal herpes is a severe disease associated with a high degree of morbidity and mortality and long-term serious consequences in survivors. Neonatal herpes presents in several different forms: skin, eye, and mucosal membrane disease, central nervous system (CNS) disease, and disseminated disease. Early diagnosis and treatment with antiviral therapy can be highly successful in many cases. There is a clear need for physicians who provide clinical care and counseling to pregnant women and neonates to understand the epidemiology of herpes infection and to better diagnose and manage it. The purpose of this review is to provide healthcare professionals with information that will be of practical use in dealing with patients who may have this infection. Learning Objectives This review is intended for physicians who provide clinical care and counseling to pregnant women or neonates. Upon completion of this continuing ...

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