Finasteride in the treatment of men with frontal male pattern hair loss
Source: www.hairlosstalk.com
Topic: Hair Loss
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Sort Desciption: This study evaluated the efficacy of finasteride 1 mg/day in men with frontal (anterior/mid) scalp hair thinning. ...
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Finasteride, a specific inhibitor of type 11 5a-reductase, decreases serum and scalp dihydrotestosterorie and has been shown to be effective in men with vertex male pattem hair loss.
Objective: This study evaluated the efficacy of finasteride 1 mg/day in men with frontal (anterior/mid) scalp hair thinning.
Methods: This was a 1-year, double-blind, placebo-controlled study followed by a 1-year open extension. Efficacy was assessed by hair counts (I CM2 circular area), patient and investigator assessments, and global photographic review. Results: There was a significant increase in hair count in the frontal scalp of finasteridetreated patients (P < .00 1), as well as significant improvements in patient, investigator, and global photographic assessments. Efficacy was maintained or improved throughout the second year of the study. Finasteride was generally well tolerated. Conclusion: In men with hair loss in the anterior/mid area of the scalp, finasteride 1 mg/day slowed hair loss and increased hair growth. Male pattern hair loss, or androgenetic alopecia, is a common condition with both genetic and hormonal origins. Typically, there is progressive loss and thinning of hair in an easily recognizable pattem of bitemporal and anterior/mid scalp recession or vertex thinning. ...
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