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Vitamin C Physiological Functions

Source: www.feinberg.northwestern.edu
Topic: Vitamins
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Sort Desciption: Vitamin C (ascorbic acid) is a water-soluble antioxidant that is responsible for maintaining iron in its reduced state thus preserving activity of the hundreds of enzymes that contain iron at the catalytic site.

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Vitamin C (ascorbic acid) is a water-soluble antioxidant that is responsible for maintaining iron in its reduced state thus preserving activity of the hundreds of enzymes that contain iron at the catalytic site. The most well-documented of these enzymes are the iron-containing prolyl and lysyl hydroxylases that catalyze the post-translational hydroxylation of proline and lysine. Hydroxyproline and hydroxylysine provide sites for cross-linking of collagen fibrils responsible for tensile strength and elasticity in connective tissue. Tissues most sensitive to Vitamin C status are those which contain large amounts of collagen such as blood vessels and capillaries, bone, and scar tissue. Vitamin C dependent reactions cover a broad range of functions that include phagocytic activity, neurotransmitter synthesis, and hepatic production of bile from cholesterol.

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