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EDN 87


image: EDN 87

Source: www.echotech.org
Topic: Kwashiorkor
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Sort Desciption: A relationship of some kind seems to exist between aflatoxin and kwashiorkor (a form of malnutrition caused by inadequate protein intake). Children with kwashiorkor have been found to have increased concentrations of aflatoxin in their body ...

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A relationship of some kind seems to exist between aflatoxin and kwashiorkor (a form of malnutrition caused by inadequate protein intake). Children with kwashiorkor have been found to have increased concentrations of aflatoxin in their body fluids than both healthy children and children with other diseases of malnourishment. However, it is not yet known if exposure to aflatoxin actually results in the development of kwashiorkor. The higher levels and more frequent presence of aflatoxin in kwashiorkor patients might mean that they were exposed to more toxins, or it might result from a lack of ability to transport and excrete toxins. If the former is the case, researcher R.G. Hendrickse suggests that aflatoxin may damage the liver, making it unable to manufacture the protein albumin. Low levels of albumin lead to kwashiorkor. Either way, it seems clear that children with kwashiorkor are at greater risk from aflatoxin than normal children. There are also indications that the metabolism of aflatoxin differs depending on the type and incidence of malnutrition. In a study by Hendrickse, a metabolite of aflatoxin B1 was detected in people with kwashiorkor (12%) and with marasmic-kwashiorkor (6%) but only once in a person with marasmus (a form of malnutrition resulting from insufficient energy intake) and not in people with adequate nutrition. ...

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