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Pathophysiology of Nephrotoxic Acute Renal Failure

Source: www.kidneyatlas.org
Topic: Acute kidney failure
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Sort Desciption: 15 Pathophysiology of Nephrotoxic Acute Renal Failure H umans are exposed intentionally and unintentionally to a variety of diverse chemicals that harm the kidney.

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Humans are exposed intentionally and unintentionally to a variety of diverse chemicals that harm the kidney. As the list of drugs, natural products, industrial chemicals and environmental pollutants that cause nephrotoxicity has increased, it has become clear that chemicals with very diverse chemical structures produce nephrotoxicity. For example, the heavy metal HgCl 2 , the mycotoxin fumonisin B 1 , the immunosuppresant cyclosporin A, and the aminoglycoside antibiotics all produce acute renal failure but are not structurally related.

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