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NCI Cancer Bulletin

Source: www.cancer.gov
Topic: Tailbone
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Sort Desciption: Chordoma is a rare bone tumor at the base of the skull, in the vertebra, or in the area of the tailbone. Only about 300 cases are diagnosed in the U.S. each year. ...

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Chordoma is a rare bone tumor at the base of the skull, in the vertebra, or in the area of the tailbone. Only about 300 cases are diagnosed in the U.S. each year. While most people with chor- doma have no other family members with the disease, rare occurrences of multiple cases within families have been documented. This suggests that some people may be genetically predisposed to develop chordoma. Because genetic or hereditary risk fac- tors for chordoma may exist, scientists are searching for genes involved in the development of this tumor. NCI is seeking families with two or more relatives with chordoma to par- ticipate in this study. Participants will complete a questionnaire, provide a blood sample, and undergo magnetic resonance imaging (MRI) scans. ...

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