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Clinical Guidelines: Prostate Cancer

Source: www.cancerboard.ab.ca
Topic: Prostate
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Sort Desciption: Standard method of detection for prostate cancer ... In early stage prostate cancer, a needle biopsy to confirm a diagnosis is standard and is most ...

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The standard methods of detection for prostate cancer are the digital rectal examination (DRE) and measurement of the serum prostate specific antigen (PSA), which should be done in fit men between 50 and 70 years of age where clinically indicated (ADD AMA guidelines re frequency of testing). Although there is good evidence that it increases the detection rate of early stage clinically significant prostate cancers, there is no evidence to date that such early detection leads to reduced mortality; the gold standard for early detection tests. Fit men age between the ages of 50 and 75 with at least ten years life expectancy should be made aware of the availability of PSA as a detection test for prostate cancer. They should be aware of the potential benefits and risks of early detection so they can make an informed decision as to whether to have the test performed. Elevated PSA and/or abnormal DRE are not diagnostic of prostate cancer; they do serve to risk stratify patients. In early stage prostate cancer, a needle biopsy to confirm a diagnosis is standard and is most accurate when done using ultrasound guided sextant biopsies. Indications for biopsies include a clinical suspicion of prostate cancer based on the PSA and DRE findings. Definitions Primary tumor (T) TX: Primary ...

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