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CRC - Bile Duct _Cholangiocarcinoma_ Cancer

Source: www.cancer.org
Topic: Bile duct
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Sort Desciption: The bile duct is a thin tube, about 4 to 5 inches long, that reaches from the liver to the small intestine. In the liver, it begins as many small channels that gather bile from the liver cells. ...

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What Is Bile Duct Cancer? The bile duct is a thin tube, about 4 to 5 inches long, that reaches from the liver to the small intestine. In the liver, it begins as many small channels that gather bile from the liver cells. These all join into one tube or duct (this part of the bile duct is called the hepatic duct). About one-third along the length of the bile duct, the gallbladder attaches by a small duct called the cystic duct. The combined duct is called the common bile duct. The end of this part of the bile duct empties into the earliest part of the small intestine, next to where the pancreatic duct also enters the small intestine. The major function of this system is to transport bile to the small intestine where it aids in digesting food. Cancers can develop in any part of the bile duct and, based on their location, are divided into three groups. Cancers beginning in these three different areas may cause different symptoms. About two-thirds of bile duct cancers develop at the part of the hepatic duct where the bile ducts have joined and are just leaving the liver. These are called perihilar cancers and were described in 1965 by Dr. Gerald Klatskin. Sometimes these perihilar tumors are called Klatskin tumors. About one-fourth of bile duct cancers are found in the in the common bile duct nearest the intestine. Doctors call these distal bile duct cancers. The rest, about 6% of the cancers, develop in the smaller bile duct branches inside the liver and are called intrahepatic (inside the liver) bile duct cancers. Over 95% of bile duct cancers are adenocarcinomas. Adenocarcinomas are cancers of glandular cells that can develop in several organs of the body. Bile duct adenocarcinomas develop from the mucus glands that line the inside of the ducts. Cholangiocarcinoma is another name for bile duct adenocarcinomas. Some doctors use this term for all bile duct adenocarcinomas. Other doctors use this term only in describing intrahepatic or hilar tumors, but not for distal bile duct cancers. ...

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