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Survival of TNF antagonists in spondylarthritis is better than in rheumatoid arthritis

Source: www.biomedcentral.com
Topic: Spondylarthritis
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Sort Desciption: The aim of the present work is to compare drug survival and safety of infliximab, etanercept, and adalimumab (tumor necrosis factor TNF antagonists) in spondylarthritis (SpA) with those of rheumatoid arthritis (RA). ...

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The aim of the present work is to compare drug survival and safety of infliximab, etanercept, and adalimumab (tumor necrosis factor TNF antagonists) in spondylarthritis (SpA) with those of rheumatoid arthritis (RA). To this purpose, we analysed the data in BIOBADASER (20002005), a drug registry launched in 2000 for long-term follow-up of the safety of these biologics in rheumatic diseases. The rates of drug discontinuation and adverse events (AEs) in SpA (n = 1,524) were estimated and compared with those of RA (n = 4,006). ...

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