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Paget's Disease from Western India

Source: www.japi.org
Topic: Paget's disease of bone
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Sort Desciption: To prospectively study prevalence of Paget s disease from Western India. Methods and Materials: Seventeen consecutive cases from Western India from 1998 to 2005 are analysed for the clinical, biochemical, skeletal profile. Seventeen cases (15 males & 2 females) with mean age of 62 were diagnosed ...

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Pagetâ s disease of bone is characterized by an anarchic bone remodeling, associated with morphological and functional abnormalities of osteoclasts. Pagetâ s disease, as the condition came to be known, is the second most common bone disorder (after osteoporosis) in elderly persons in the Western world. Pagetâ s disease is rare in India, China and Scandinavia, but common in specifically England, Western Europe, and the United States. Affecting more than one million people, the chronic bone disorder is marked by the malfunction of the bodyâ s regular bone building process and may result in pain, deformities and fractures. The reason for its rarity amongst Indians is difficult to explain. ...

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