Hiv/Aids Atypical Moles Osteoporosis Psoriasis Clinical Depression Acne Vitiligo Phenylketonuria Tailbone Thalassemia Skin Scurvy

DETECTION OF -THALASSEMIA CARRIERS IN JORDAN

Source: www.kfshrc.edu.sa
Topic: Thalassemia
Download: Click here!

Sort Desciption: Hemoglobinopathies are a major health problem in many areas of the world. Two of the most prevalent hemoglobinopathies are sickle hemoglobin (Hb S) and thalassemia. 1,2 Thalassemia is a molecular abnormality with underproduction of one of the globin chains. ...

Content Inside:
Hemoglobinopathies are a major health problem in many areas of the world. Two of the most prevalent hemoglobinopathies are sickle hemoglobin (Hb S) and thalassemia. 1,2 Thalassemia is a molecular abnormality with underproduction of one of the globin chains. 3 Heterozygous states for -thalassemia genes, known as -thalassemia minor, are usually not associated with clinically significant disease. -thalassemia has a high prevalence in the Mediterranean area, and in the Middle and Far East. 3-6 Thalassemia screening programs have demonstrated effectiveness as antecedents to more successful management of the disease, including early intervention and prevention of complications. However, the value of screening programs has not been without controversy, due to the social and psychological impact on the individual and the family, 1 such as parental frustration, the lack of adequate information on the disease among the local population, and a cultural system which makes a carrier feel inferior. Jordan is located in an area where -thalassemia is prevalent, but no definite screening program has yet been developed. The aim of this study is to determine the real prevalence of thalassemia carriers in Jordan, using our own cutoff points, and to develop a better understanding of this disease. This should result in a more efficient utilization of health care resources and improved planning in the provision of health care services. Patients and Methods The investigation targeted 751 subjects. Of these, 249 randomly selected students of Jordan University constituted the first group. The second group comprised 502 subjects from a premarital screening program which had been adopted recently in Jordan. CBC and RBC indices were performed on all subjects using the ...

Name (required)

E-mail (required - never shown publicly)

URI (optional)

Your Comment

Verification Code

© 2007-2009 HealthPDF.org | Design by Ganesh Gunasegaran
Privacy Policy

All files and contents mentioned are the property of their respective owners. This page consists of a compilation of public information, commonly available on the internet, at multiple sites, as well as official websites. No information on this page is guaranteed to be correct, and any data contained here may be erroneous.