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Sepsis in Older Patients: An Emerging Concern in Critical Care

Source: www.advancesinsepsis.com
Topic: Sepsis
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Sort Desciption: Severe sepsis is a very common and important cause of morbidity and mortality in the older population, and its incidence has increased in the last 10 years It is estimated that about 750 000 patients per year develop severe sepsis in the US, of which nearly 60% are >65 years-of-age ...

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Severe sepsis is a very common and important cause of morbidity and mortality in the older population, and its incidence has increased in the last 10 years 1 . It is estimated that about 750 000 patients per year develop severe sepsis in the US, of which nearly 60% are >65 years-of-age 2,3 . This is also reflected in the changing demographics of intensive care units (ICUs), where nearly two-thirds of beds are occupied by those >65 years old 3 . Aging patients account for 4050% of all cases of bacteremia, and the overall case fatality rate for older patients with bacteremia ranges from 4060%, or higher when Gram-negative organisms are involved 4,5,6 . This segment of the population will increase significantly over the coming years, driving an increase in the amount of resources used on these patients, who are thought to have a shortened life span 7 . This review analyzes the characteristics of older patients, discusses the unique aspects of severe sepsis in this increasingly important segment of our society, and provides a better understanding of the special needs of these patients. We also outline areas of future research that might improve outcomes in this patient population. Methods We performed a Medline search of the literature from 1996 to September 2001, using the keywords sepsis, aged, and elderly and limiting the search to human studies and English language publications. The search identified 3159 articles, which were ...

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