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POLYCYTHEMIA VERA

Source: l3.leukemia-lymphoma.org
Topic: Polycythemia Vera
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Sort Desciption: What is polycythemia vera? Polycythemia vera, often abbreviated as PV, is a disease that results from an abnormality of a very immature cell in the bone marrow, the site in which all blood cells are made. ...

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What is polycythemia vera? Polycythemia vera, often abbreviated as PV, is a disease that results from an abnormality of a very immature cell in the bone marrow, the site in which all blood cells are made. The altered cell develops a growth advantage and produces blood cells in such large numbers that they are overrepresented in the marrow. There is some variation in this abnormality. In virtually all cases of polycythemia vera, the marrow produces too many red blood cells. In many patients, the numbers of white blood cells and blood platelets are also elevated. The increase in red cells and a reciprocal decrease in plasma can lead to blood that is thicker than normal (viscous) and does not flow normally. What is the derivation of the term polycythemia vera? The word polycythemia is composed of the Greek words poly (many), cyt (cells), and hemia (blood). Thus, it is applied to a disease in which there are too many of the principal cells (red, white, and platelets) in the blood. The term vera is from the Latin word meaning true. The latter term is used to distinguish this disorder from a host of other conditions that can result in an increase in the number of red cells in the blood. 2 Polycythemia Vera 800.955.4572 www.leukemia-lymphoma.org Formerly Leukemia Society of America What are the symptoms and signs of polycythemia vera? Polycythemia vera is detected in many patients when a periodic health examination uncovers an elevated red cell count. Patients usually experience only vague and non-specific symptoms. They may have had minor complaints, but none were sufficiently troubling to have led to a medical examination. The physician may discover an enlarged spleen through the physical examination or an imaging procedure of the abdomen. The disease also may be detected as a result of a medical examination for a blood ...

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