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Lymphatic Filariasis


image: Lymphatic Filariasis

Source: www.who.int
Topic: Filariasis
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Sort Desciption: Strategic Direction for Research Lymphatic Filariasis www.who.int/tdr Disease burden and epidemiological trends TDR Strategic Direction: Lymphatic Filariasis February 2002 Current control strategy ...

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Strategic Direction for Research Lymphatic Filariasis www.who.int/tdr Disease burden and epidemiological trends TDR Strategic Direction: Lymphatic Filariasis February 2002 Current control strategy Lymphatic filariasis is one of the most prevalent tropical diseases. It is estimated that some 120 million people are infected. Of these, 95% are infected with Wuchereria bancrofti, and the remainder with Brugia malayi or B. timori. The disease is reported to be responsible for 5 million DALYs lost annually, ranking third among the TDR diseases in terms of DALYs, after malaria and TB. India and Africa together account for 85-90% of the estimated burden of disease in terms of DALYs. Lymphatic filariasis is a major impediment to socioeconomic development (India has been estimated to lose $1 billion per year as a result of lymphatic filariasis) and is responsible for immense psychosocial suffering among the affected. The current estimates of the number of people infected are based on very limited information, especially for Africa where the distribution of the disease is hardly known and where mapping has only just begun. Furthermore, recent studies have shown that hidden lymphatic and other pathology, which is not taken into account in the DALY estimates, begins in early childhood and is common among the large number of infected persons who do not have overt clinical symptoms. Hence, estimates of the burden of lymphatic filariasis are likely to change significantly over the coming years. The epidemiological trends during the last decades have varied widely between different regions of the world. Filariasis was controlled or eradicated from several islands in the Pacific, and China has seen a dramatic reduction in infection levels. Unfortunately, in the most endemic areas of the world, notably India and Africa, there has been no decline in filariasis infection during the last 10 years and in many areas there has been an increase, often associated with ur ...

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