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Allergy and Multiple Chemical Sensitivities Distinguished

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Topic: Chemicals
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Sort Desciption: Allergy and Multiple Chemical Sensitivities ... ALLERGY & MULTIPLE CHEMICAL SENSITIVITY ... Alternative Approach to Allergies. New. York: Harper ...

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Allergy and Multiple Chemical Sensitivities Distinguished. When von Pirquet coined the term allergy in 1906, he defined it as altered reactivity. Thus the word allergy as originally conceived encompassed both immunity and hypersensitivity. In 1925 European allergists influenced their American colleagues to redefine Allergy in the context of antibodies and antigens, effectively excluding hypersensitivity on any other basis. Forty years ago, Theron Randolph, a classically trained allergist, noted that a cosmetic saleswoman he had been seeing for rhinitis, asthma, headache, fatigue, irritability, depression, marked weight fluctuation and intermittent episodic loss of consciousness developed her symptoms following exposure to gas, oil, coal and their combustion products (Randolph, 1987, pp. 73-76). Randolph developed a diagnostic-therapeutic maneuver which consisted of removing the patient from all suspected environmental exposures and subsequently reintroducing single elements of the environment one at a time, while observing for changes in the patients condition (Randolph, 1960). Although what he observed in his patients appeared to be some kind of hypersensitivity, it was not allergy. Subsequently, Randolph and other physicians known as clinical ecologists published clinical descriptions of patients with polysomatic complaints, frequently including mood and cognition difficulties, triggered by a wide variety of chemical exposures, but especially petrochemical exposures, and often with concomitant food and drug intolerances. These clinical descriptions bear striking resemblance to todays MCS patients, many of whom have never heard of clinical ecology. A review of the literature on exposure to low levels of chemicals reveals four groups or clusters of people among whom individuals with heightened reactivity have been reported (Ashford and Miller ...

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