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Biosafety Facts

Source: www.ehs.uiuc.edu
Topic: Animals
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Sort Desciption: allergies. What is a laboratory animal allergy? Laboratory animal allergy (LAA) may develop when susceptible persons are exposed ...

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Biosafety Facts Biosafety Facts Division of Research Safety University of Illinois at Urbana-Champaign September 2005 Laboratory Animal Allergy What is an allergy? An allergy is an extreme sensitivity to a usually harmless substance, such as food, dust, or pollen. About 20% of Americans suffer from an allergic disease. Persons suffering from allergies often experience symptoms such as itchy, watery eyes, sneezing, or an itchy, runny nose. Skin rashes and hives or more severe symptoms such as wheezing and shortness of breath may also occur. Asthma, a serious disease that limits the affected persons ability to breathe, is most commonly triggered by allergies. What is a laboratory animal allergy? Laboratory animal allergy (LAA) may develop when susceptible persons are exposed to allergens produced by laboratory animals. LAA is most associated with exposure to fur, saliva, and urine of rats, mice, guinea pigs, and rabbits. Approximately 30% of persons who are exposed to lab animals develop LAA; some of these persons will also develop asthma. LAA is most likely to occur in persons with previously known allergies, especially to domestic pets; however, more than a third of the persons developing LAA do not report any previous allergies. The majority of LAA sufferers experience symptoms within six months of their first exposure to lab animals; almost all develop symptoms within four years. Unfortunately, LAA may also affect persons who have never been exposed to lab animals. The allergens are sticky and may be carried on an exposed persons hair or clothing. In this way, non-exposed coworkers may be sensitized to the allergens and develop LAA. What are the symptoms of LAA and how can I prevent them? The allergens that cause LAA are potent. Exposure to one-millionth of a gram may trigger symptoms. Symptoms generally occur within ten minutes of exposure. The most common symptoms are itchy, watery eyes and an itchy, runny nose, although skin symptoms and lower respiratory symp ...

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